SCHEMBL2482401

SCHEMBL2482401

CCc1cccc(-c2cccc(-c3ccccn3)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.54
IDO1 P14902 1/20 0.50
FFAR1 O14842 1/20 0.46
NISCH Q9Y2I1 1/20 0.45
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP19A1 P11511 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
BCL2 P10415 1/20 0.44
CTSS P25774 2/20 0.44
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
CYP2A6 P11509 1/20 0.43
HIF1A Q16665 2/20 0.43
CTSK P43235 1/20 0.43
HTR1A P08908 1/20 0.42
HTR7 P34969 1/20 0.42
HCRTR1 O43613 4/20 0.42
HCRTR2 O43614 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8270139 0.97 HRH3 (0.56) HRH3IDO1FFAR1NISCHCYP1A2
SCHEMBL17834278 0.93 HRH3 (0.50) HRH3IDO1FFAR1NISCHCYP1A2
SCHEMBL13799177 0.92 HRH3 (0.49) HRH3IDO1FFAR1NISCHCYP1A2
SCHEMBL28426269 0.89 CYP1A2 (0.46) HRH3FFAR1CYP1A2CYP2D6CYP19A1
SCHEMBL19559907 0.86 CYP1A2 (0.49) HRH3CYP1A2CYP2D6CYP19A1CYP2C9
SCHEMBL21506994 0.84 KDM4E (0.59) HRH3CYP1A2CYP2A6HIF1AHTR1A
SCHEMBL4472579 0.83 HRH3 (0.54) HRH3FFAR1CYP1A2CYP2D6CYP19A1
SCHEMBL26210101 0.83 CYP1A2 (0.44) HRH3FFAR1CYP1A2CYP2D6CYP19A1
SCHEMBL649582 0.83 HRH3 (0.50) HRH3FFAR1CYP1A2CTSSCTSL
SCHEMBL16203116 0.82 CYP1A2 (0.48) HRH3FFAR1CYP1A2CYP2D6CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3855519-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2021-07-28 EP disclosed
EP-3428986-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2021-01-20 EP disclosed
EP-3428986-A1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2019-01-16 EP disclosed
EP-1763902-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2018-08-29 EP disclosed
US-8603645-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-12-10 US disclosed
EP-2378582-A1 Stable and efficient electroluminescent materials Universal Display Corporation (US) 2011-10-19 EP disclosed
US-20110060143-A1 Stable and Efficient Electroluminescent Materials KWONG RAYMOND 2011-03-10 US disclosed
US-7851072-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2010-12-14 US disclosed
CN-101076902-B Stable and effective electroluminescent material UNIVERSAL DISPLAY CORP 2010-07-28 CN disclosed
CN-101076902-A Stable and effective electroluminescent material UNIVERSAL DISPLAY CORP (US) 2007-11-21 CN disclosed
EP-1763902-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2007-03-21 EP disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110060143-A1 Stable and Efficient Electroluminescent Materials EML4, ITGA5, CHRM5 HRH3 1507/4885IDO1 1851/4885FFAR1 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.