Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24824337 | 0.82 | TLR7 (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29113595 | 0.82 | TLR7 (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31349381 | 0.78 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2LMNACASP3 | |
| SCHEMBL30097204 | 0.76 | CHRNA7 (0.43) | RAB9ANPC1LMNAALDH1A1MAPT | |
| SCHEMBL18344137 | 0.75 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL791700 | 0.75 | MAPT (0.46) | LMNACASP3ALDH1A1MAPTMEN1 | |
| SCHEMBL12006634 | 0.75 | MAPT (0.46) | LMNACASP3ALDH1A1MAPTMEN1 | |
| SCHEMBL12006635 | 0.75 | MAPT (0.46) | LMNACASP3ALDH1A1MAPTMEN1 | |
| SCHEMBL4700525 | 0.74 | HTR3A (0.60) | CHRNB4CHRNA3 | |
| SCHEMBL31349462 | 0.74 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2LMNACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268154-A1 | NEW ANTI-HEPATITIS B COMPOUND | 上海齐鲁制药研究中心有限公司 | 2022-12-29 | — | — | WO | disclosed |