Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15704199 | 0.84 | CACNB4 (0.41) | CYP19A1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL16727205 | 0.84 | PTGER4 (0.43) | PTGER4CYP19A1KCNH2MAPTCYP2C19 | |
| SCHEMBL18015838 | 0.82 | KCNH2 (0.56) | PTGER4CYP19A1KCNH2MAPTCYP2C19 | |
| SCHEMBL13153267 | 0.82 | PTGER4 (0.42) | PTGER4CYP19A1KCNH2MAPTCYP2C19 | |
| SCHEMBL24823829 | 0.82 | CYP19A1 (0.43) | CYP19A1KCNH2MAPTL3MBTL1KDM4E | |
| SCHEMBL15701668 | 0.80 | RORA (0.38) | CYP19A1MAPTCYP2C19HTR6CNR1 | |
| SCHEMBL10095354 | 0.78 | SMN1; SMN2 (0.50) | TDP1KDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL22450720 | 0.78 | PTGER4 (0.52) | PTGER4CYP19A1KCNH2MAPTTDP1 | |
| SCHEMBL24182136 | 0.77 | KCNH2 (0.56) | PTGER4CYP19A1KCNH2MAPTCYP2C19 | |
| SCHEMBL22450724 | 0.77 | KCNH2 (0.56) | PTGER4KCNH2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |