SCHEMBL24825719

SCHEMBL24825719

c1ccc(-c2ccc(-c3ccc(N(c4cccc(-c5cc6ccccc6c6ccccc56)c4)c4cccc5c4ccc4c6ccccc6oc54)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
CYP1A1 P04798 4/20 0.34
CYP1A2 P05177 4/20 0.34
CYP1B1 Q16678 4/20 0.34
PRKDC P78527 2/20 0.32
GGPS1 O95749 1/20 0.32
CYP11B1 P15538 1/20 0.32
GPR84 Q9NQS5 2/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
MAOB P27338 1/20 0.30
RAB9A P51151 1/20 0.30
PDE5A O76074 1/20 0.30
TP53 P04637 1/20 0.30
ABCB1 P08183 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24825281 0.95 ALOX5 (0.38) ALOX5CYP1A1CYP1A2CYP1B1PRKDC
SCHEMBL26020262 0.94 ALOX5 (0.37) ALOX5CYP1A1CYP1A2CYP1B1PRKDC
SCHEMBL24825710 0.94 ALOX5 (0.39) ALOX5CYP1A1CYP1A2CYP1B1PRKDC
SCHEMBL24825716 0.91 ALOX5 (0.40) ALOX5CYP1A1CYP1A2CYP1B1PRKDC
SCHEMBL24825722 0.91 ALOX5 (0.37) ALOX5CYP1A1CYP1A2CYP1B1PRKDC
SCHEMBL26020251 0.91 ALOX5 (0.36) ALOX5CYP1A1CYP1A2CYP1B1GGPS1
SCHEMBL24887947 0.91 ALOX5 (0.36) ALOX5CYP1A1CYP1A2CYP1B1GGPS1
SCHEMBL24825288 0.90 CYP1A1 (0.39) ALOX5CYP1A1CYP1A2CYP1B1PRKDC
SCHEMBL23822521 0.90 ALOX5 (0.37) ALOX5CYP1A1CYP1A2CYP1B1GGPS1
SCHEMBL24825407 0.90 ALOX5 (0.42) ALOX5CYP1A1CYP1A2CYP1B1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed