SCHEMBL24825710

SCHEMBL24825710

c1ccc(-c2ccc(-c3ccc(N(c4cccc(-c5cc6ccccc6c6ccccc56)c4)c4cc5c6ccccc6oc5c5ccccc45)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
GGPS1 O95749 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP1B1 Q16678 1/20 0.32
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MPI P34949 1/20 0.32
KMT2A Q03164 1/20 0.32
GPR84 Q9NQS5 2/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
PRKDC P78527 1/20 0.31
AHR P35869 1/20 0.30
MAOB P27338 1/20 0.30
RAB9A P51151 1/20 0.30
PLA2G2A P14555 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24887947 0.97 ALOX5 (0.36) ALOX5GGPS1CYP11B1CYP1A1CYP1A2
SCHEMBL26020251 0.97 ALOX5 (0.36) ALOX5GGPS1CYP11B1CYP1A1CYP1A2
SCHEMBL24825719 0.94 ALOX5 (0.39) ALOX5GGPS1CYP11B1CYP1A1CYP1A2
SCHEMBL24825487 0.93 KDM4E (0.37) ALOX5CYP11B1CYP1A1CYP1A2CYP1B1
SCHEMBL24586382 0.92 HSD17B1 (0.34) ALOX5CYP11B1CYP1A1CYP1A2CYP1B1
SCHEMBL26020235 0.92 ALOX5 (0.35) ALOX5CYP11B1CYP1A1CYP1B1KDM4E
SCHEMBL24825827 0.91 ALOX5 (0.43) ALOX5GGPS1CYP1A1CYP1A2CYP1B1
SCHEMBL17126613 0.90 ALOX5 (0.47) ALOX5GGPS1CYP1A1CYP1A2CYP1B1
SCHEMBL10110253 0.90 ALOX5 (0.47) ALOX5GGPS1CYP1A1CYP1A2CYP1B1
SCHEMBL24825651 0.90 ALOX5 (0.38) ALOX5GGPS1CYP11B1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed