SCHEMBL24825766

SCHEMBL24825766

c1ccc2c(N(c3ccc(-n4c5ccccc5c5ccccc54)cc3)c3cccc4ccc5c6ccccc6oc5c34)cccc2c1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24825767 0.97 L3MBTL1 (0.31) L3MBTL1KDM4EATMTDP1
SCHEMBL24827025 0.92 KDM4E (0.36) L3MBTL1KDM4EATMTDP1ALDH1A1
SCHEMBL24827006 0.91 MEN1 (0.35) L3MBTL1KDM4EATMMEN1ALDH1A1
SCHEMBL24826855 0.91 ERBB2 (0.31) L3MBTL1KDM4EATM
SCHEMBL24825760 0.91 ERBB2 (0.31) L3MBTL1KDM4EATMTDP1
SCHEMBL18267631 0.90 L3MBTL1 (0.32) L3MBTL1KDM4EATMTDP1MEN1
SCHEMBL24827002 0.90 MEN1 (0.33) L3MBTL1KDM4EATMMEN1ALDH1A1
SCHEMBL24825789 0.90 KDM4E (0.34) L3MBTL1KDM4EATMMEN1ALDH1A1
SCHEMBL24825768 0.90 ALDH1A1 (0.32) L3MBTL1KDM4EATMTDP1MEN1
SCHEMBL24827026 0.89 KDM4E (0.34) L3MBTL1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416174-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-29 US disclosed