Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.46 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24825907 | 0.78 | AR (0.48) | BCAT2BCAT1ARPKMSMN1; SMN2 | |
| SCHEMBL30046063 | 0.73 | LMNA (0.49) | BCAT2BCAT1ARSMN1; SMN2MEN1 | |
| SCHEMBL395415 | 0.73 | ALDH1A1 (0.54) | ARSMN1; SMN2MEN1NPC1TSHR | |
| SCHEMBL29597724 | 0.73 | ALDH1A1 (0.54) | ARSMN1; SMN2MEN1NPC1TSHR | |
| SCHEMBL29779327 | 0.72 | MEN1 (0.47) | BCAT2BCAT1ARSMN1; SMN2MEN1 | |
| SCHEMBL24826943 | 0.72 | MEN1 (0.47) | BCAT2BCAT1ARSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL10424097 | 0.72 | SMN1; SMN2 (0.47) | ARSMN1; SMN2MEN1NPC1TSHR | |
| SCHEMBL29637724 | 0.72 | TSHR (0.65) | ARSMN1; SMN2MEN1NPC1TSHR | |
| SCHEMBL127000 | 0.72 | TSHR (0.65) | ARSMN1; SMN2MEN1NPC1TSHR | |
| SCHEMBL25500740 | 0.70 | AR (0.60) | ARSMN1; SMN2MEN1NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411381-A1 | PYRIMIDINEDIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411381-A1 | PYRIMIDINEDIONE DERIVATIVES | DPYD, TYMP, TYMS | BCAT2 3754/4885BCAT1 2999/4885AR 2511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.