SCHEMBL24827960

SCHEMBL24827960

CC(C)c1cnc(N2CCN(C(C)(C)C)CC2)nc1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 16/20 0.40
▸ PANK3 Q9H999 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ LMNA P02545 1/20 0.34
▸ HTR3A P46098 1/20 0.34
▸ HRH4 Q9H3N8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24827911 0.82 CYP3A4 (0.35) OGAPANK3
SCHEMBL20225831 0.80 OGA (0.41) OGAKDM4ENPC1RAB9ALMNA
SCHEMBL11402241 0.80 HRH4 (0.47) OGAPANK3LMNAHTR3AHRH4
SCHEMBL19105574 0.80 PANK3 (0.40) OGAPANK3KDM4ENPC1RAB9A
SCHEMBL13466910 0.80 PANK3 (0.40) OGAPANK3LMNA
SCHEMBL19001135 0.79 OGA (0.44) OGAPANK3
SCHEMBL17037512 0.79 SIGMAR1 (0.43) OGAKDM4E
SCHEMBL10140525 0.79 PANK3 (0.41) OGAPANK3KDM4ENPC1RAB9A
SCHEMBL21025738 0.79 HTR3A (0.36) OGAKDM4ENPC1RAB9ALMNA
SCHEMBL1505703 0.79 PANK3 (0.41) OGAPANK3KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542266-B1 Substituted piperidines as BTK inhibitors HAISCO PHARMACEUTICALS PTE. LTD. (SG) 2023-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11542266-B1 Substituted piperidines as BTK inhibitors BTK, BLK, SYK OGA 1689/4885PANK3 612/4885KDM4E 729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback