Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16060069 | 1.00 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL985927 | 1.00 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL4178282 | 0.94 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL18269655 | 0.94 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL31356503 | 0.89 | — | — | |
| SCHEMBL10878763 | 0.88 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL2481405 | 0.88 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL2397130 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| Hydrochloric Acid SCHEMBL11622152 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 | |
| SCHEMBL2399889 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| EP-2385109-B1 | A group of esterases for the enantioselective production of fine and speciality chemicals | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2015-12-02 | — | — | EP | disclosed |
| EP-2377930-B1 | A group of esterases for the enantioselective production of fine and speciality chemicals | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-9193961-B2 | Polynucleotides encoding enantioselective carboxylesterases and methods of making same | B.R.A.I.N. AG (DE) | 2015-11-24 | — | — | US | disclosed |
| EP-2013337-B1 | A GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2385109-A2 | A group of esterases for the enantioselective production of fine and speciality chemicals | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2011-11-09 | — | — | EP | disclosed |
| EP-2377930-A1 | A group of esterases for the enantioselective production of fine and speciality chemicals | B.R.A.I.N. Biotechnology Research And Information Network AG (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20090311745-A1 | GROUP OF ESTERASES FOR THE ENANTIOSELECTIVE PRODUCTION OF FINE AND SPECIALITY CHEMICALS | B.R.A.I.N AG (DE) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | ALDH1A1 3285/4885SMN1; SMN2 2830/4885LMNA 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.