Kyotorphin

Kyotorphin

SCHEMBL248288

N=C(N)NCCC[C@H](NC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.62
NPY1R P25929 9/20 0.62
NPY5R Q15761 8/20 0.62
NPY2R P49146 5/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kyotorphin SCHEMBL2889815 1.00 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
D[-Arg-2]Kyotorphan Acetate SCHEMBL29780328 1.00 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
Kyotorphin SCHEMBL248289 1.00 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30198606 0.98 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31155494 0.97 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29613396 0.97 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31729537 0.96 NPY4R (0.69) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31575310 0.95 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL13563452 0.95 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL18951657 0.95 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1361857-A4 MODULATED RELEASE PARTICLES FOR AEROSOL DELIVERY KOS LIFE SCIENCES INC (US) 2009-07-22 EP claimed
EP-1307243-A4 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY INC (US) 2009-04-29 EP claimed
EP-1305053-A4 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY INC (US) 2009-04-29 EP claimed
EP-1361857-A1 MODULATED RELEASE PARTICLES FOR AEROSOL DELIVERY Aeropharm Technology Incorporated (US) 2003-11-19 EP claimed
EP-1307243-A2 A MEDICINAL AEROSOL FORMULATION Aeropharm Technology Incorporated (US) 2003-05-07 EP claimed
EP-1305053-A1 A MEDICINAL AEROSOL FORMULATION Aeropharm Technology Incorporated (US) 2003-05-02 EP claimed
EP-1292283-A1 A MEDICINAL AEROSOL FORMULATION Aeropharm Technology Incorporated (US) 2003-03-19 EP claimed
EP-1292283-A4 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY INC (US) 2003-03-19 EP claimed
WO-2002066008-A1 MODULATED RELEASE PARTICLES FOR AEROSOL DELIVERY AEROPHARM TECHNOLOGY, INC. (US) 2002-08-29 WO claimed
WO-2001082980-A1 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-11-08 WO claimed
WO-2001082868-A2 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-11-08 WO claimed
WO-2001082873-A2 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-11-08 WO claimed
WO-2001060420-A1 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-08-23 WO claimed
CN-108588035-A Virus or the Novel stabilisation method of bacterium 白血球保健股份有限公司 2018-09-28 CN disclosed
CN-105342994-B Infusion preparation 株式会社大塚制药工场 2018-08-07 CN disclosed
CN-107708704-A Microorganism group conditioning agent and its associated uses 卡莱多生物科技有限公司 2018-02-16 CN disclosed
WO-2001054664-A1 A METHOD OF ADMINISTERING A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-08-02 WO disclosed
EP-0278787-B1 A process for enzymatic production of dipeptides CARLBIOTECH LTD AS (DK) 1993-10-20 EP disclosed
WO-1988006187-A1 A PROCESS FOR ENZYMATIC PRODUCTION PRODUCTION OF DIPEPTIDES CARLSBERG BIOTECHNOLOGY LTD. A/S (DK) 1988-08-25 WO disclosed
EP-0278787-A1 A process for enzymatic production of dipeptides CARLBIOTECH LTD. A/S (DK) 1988-08-17 EP disclosed