Kyotorphin

Kyotorphin

SCHEMBL248289

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.62
NPY1R P25929 9/20 0.62
NPY5R Q15761 8/20 0.62
NPY2R P49146 5/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Kyotorphin SCHEMBL2889815 1.00 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
Kyotorphin SCHEMBL248288 1.00 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
D[-Arg-2]Kyotorphan Acetate SCHEMBL29780328 1.00 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30198606 0.98 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31155494 0.97 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29613396 0.97 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31729537 0.96 NPY4R (0.69) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31575310 0.95 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL13563452 0.95 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL18951657 0.95 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747264-A1 MICELLAR BIOACTIVE COLLAGEN-STIMULATING LIPOPEPTIDE University of Reading (GB) 2026-05-27 EP claimed
WO-2026105061-A1 ANTIBODY-DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2026-05-21 WO claimed
WO-2026088246-A1 METHOD FOR PRODUCING LOW-MOLECULAR-WEIGHT COMPOUND NTT株式会社 2026-04-30 WO claimed
US-20260027226-A1 ANTIBODY-DRUG CONJUGATES PHEON THERAPEUTICS LTD (GB) 2026-01-29 US claimed
EP-4594520-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2025-08-06 EP claimed
WO-2025149667-A1 ANTIBODY DRUG CONJUGATES AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2025-07-17 WO claimed
EP-4585606-A1 OLIGOPEPTIDE AND USE AND COMPOSITION THEREOF Buddhist Tzu Chi Medical Foundation (TW) 2025-07-16 EP claimed
WO-2025120085-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 WO claimed
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES HEIDELBERG PHARMA RESEARCH GMBH (DE) 2025-06-12 US claimed
EP-4554623-A1 ANTIBODY DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF Pheon Therapeutics Ltd (GB) 2025-05-21 EP claimed
US-20020110525-A1 Modulated release particles for lung delivery KOS LIFE SCIENCES, INC. 2002-08-15 US claimed
WO-2002005785-A1 MODULATED RELEASE THERAPEUTIC AEROSOLS AEROPHARM TECHNOLOGY INCORPORATED (US) 2002-01-24 WO claimed
WO-2001082980-A1 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-11-08 WO claimed
WO-2001082868-A2 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-11-08 WO claimed
WO-2001082873-A2 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-11-08 WO claimed
WO-2001060420-A1 A MEDICINAL AEROSOL FORMULATION AEROPHARM TECHNOLOGY, INC. (US) 2001-08-23 WO claimed
EP-0666729-A1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1995-08-16 EP claimed
WO-1994009750-A1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1994-05-11 WO claimed
US-5122515-A Injecting dipeptide of tyrosine and arginine mixed with other nutrients BAXTER INTERNATIONAL INC. 1992-06-16 US claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186606-A1 MODULAR LINKER COMPOUND FOR TARGET-BINDING DRUG CONJUGATES BCR, TBCD, TBC1D5 NPY4R 4623/4885NPY1R 4687/4885NPY5R 4476/4885
US-20020110525-A1 Modulated release particles for lung delivery MUC1, CD44, CHMP4B NPY4R 3130/4885NPY1R 2912/4885NPY5R 2188/4885
US-20260027226-A1 ANTIBODY-DRUG CONJUGATES SLC3A2, MTCL3, SLC13A2 NPY4R 2467/4885NPY1R 1735/4885NPY5R 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.