SCHEMBL30198606

SCHEMBL30198606

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.66
▸ NPY1R P25929 9/20 0.66
▸ NPY5R Q15761 8/20 0.66
▸ NPY2R P49146 5/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31729537 0.98 NPY4R (0.69) NPY4RNPY1RNPY5RNPY2R
Kyotorphin SCHEMBL248289 0.98 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
D[-Arg-2]Kyotorphan Acetate SCHEMBL29780328 0.98 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
Kyotorphin SCHEMBL2889815 0.98 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
Kyotorphin SCHEMBL248288 0.98 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL13563452 0.97 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31155494 0.97 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL18951657 0.97 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30274541 0.95 NPY4R (0.63) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29637467 0.95 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118853640-A Carbapenem drug-resistant gene and application thereof 郑州大学 2024-10-29 — — CN disclosed
EP-3215172-B1 MODIFICATIONS AND USES OF CONOTOXIN PEPTIDES KINETA CHRONIC PAIN LLC (US) 2023-04-26 — — EP disclosed
US-11618772-B2 Modifications and uses of conotoxin peptides KINETA CHRONIC PAIN, LLC 2023-04-04 — — US disclosed
US-11566256-B2 Polynucleotides and polypeptides in plants MENDEL BIOTECHNOLOGY, INC. (US) 2023-01-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11618772-B2 Modifications and uses of conotoxin peptides CHRNA9, CHRNA10, CHRNA7 NPY4R 130/4885NPY1R 139/4885NPY5R 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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