⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19084110 | 0.68 | — | — | |
| SCHEMBL21941055 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL25478223 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL13748479 | 0.65 | TP53 (0.33) | — | |
| SCHEMBL22314222 | 0.65 | — | — | |
| SCHEMBL18629959 | 0.65 | — | — | |
| SCHEMBL20630677 | 0.64 | CYP1A2 (0.30) | — | |
| SCHEMBL23552547 | 0.64 | — | — | |
| SCHEMBL13184339 | 0.64 | TP53 (0.32) | — | |
| SCHEMBL21132951 | 0.64 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158166-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | SUTURA THERAPEUTICS LTD (GB) | 2023-05-25 | — | — | US | disclosed |
| US-11541124-B2 | Biologically active compound conjugated to a stapled or stitched peptide | SUTURA THERAPEUTICS LTD (TC) | 2023-01-03 | — | — | US | disclosed |