Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | KLK7 | P49862 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SCD | O00767 | 8/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482989 | 0.86 | SCD (0.72) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2483241 | 0.84 | SCD (0.84) | ALDH1A1MAP3K5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12422014 | 0.84 | MAPT (0.66) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13329390 | 0.84 | MAP3K5 (0.83) | ALDH1A1MAPTGAAMAP3K5NPC1 | |
| SCHEMBL12199362 | 0.82 | MAP3K5 (0.76) | ALDH1A1MAPTMAP3K5NPC1RAB9A | |
| SCHEMBL12199335 | 0.82 | MAP3K5 (0.76) | ALDH1A1MAPTMAP3K5NPC1RAB9A | |
| SCHEMBL4917536 | 0.81 | SMN1; SMN2 (0.81) | ALDH1A1MAPTCYP2C19NPC1RAB9A | |
| SCHEMBL3348202 | 0.81 | LMNA (0.62) | ALDH1A1MAPTCYP2C19NPC1RAB9A | |
| SCHEMBL2483622 | 0.81 | MAP3K5 (0.77) | ALDH1A1MAPTGAAMAP3K5NPC1 | |
| SCHEMBL4913650 | 0.80 | SCD (0.88) | ALDH1A1MAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376463-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | Bayer Pharma Aktiengesellschaft (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110243846-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-10-06 | — | — | US | disclosed |
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110243846-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | APP, APBA1, BACE1 | ALDH1A1 2731/4885MAPT 5/4885GAA 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.