Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | RAB9A | P51151 | 8/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | SCD | O00767 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482989 | 0.84 | SCD (0.72) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL2481628 | 0.82 | SMN1; SMN2 (0.74) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL2514126 | 0.81 | MAPT (0.70) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL2483129 | 0.81 | ALDH1A1 (0.68) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL3648836 | 0.80 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL18154178 | 0.80 | DYRK1A (0.79) | LMNASMN1; SMN2NPC1RAB9AHSD17B10 | |
| SCHEMBL30101680 | 0.79 | SMN1; SMN2 (0.78) | SMN1; SMN2NPC1RAB9AMAPTTP53 | |
| SCHEMBL3655027 | 0.78 | CSNK1D (0.57) | LMNASMN1; SMN2NPC1RAB9AHSD17B10 | |
| Tioxidazole SCHEMBL23382 | 0.77 | LMNA (1.00) | LMNASMN1; SMN2NPC1RAB9AHSD17B10 | |
| Tioxidazole SCHEMBL1033860 | 0.77 | LMNA (1.00) | LMNASMN1; SMN2NPC1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |