Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2486872 | 1.00 | KMT2A (0.58) | KMT2AMEN1ELANEMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2486670 | 0.98 | KMT2A (0.56) | KMT2AMEN1ELANEMAPTALDH1A1 | |
| SCHEMBL9290108 | 0.90 | KMT2A (0.47) | KMT2AMEN1ELANEMAPTALDH1A1 | |
| SCHEMBL28529501 | 0.89 | ALDH1A1 (0.60) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL2485289 | 0.89 | KMT2A (0.50) | KMT2AMEN1ELANEMAPTALDH1A1 | |
| SCHEMBL2485286 | 0.89 | KMT2A (0.50) | KMT2AMEN1ELANEMAPTALDH1A1 | |
| SCHEMBL2482095 | 0.89 | ALDH1A1 (0.56) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL1695890 | 0.85 | KDM4E (0.56) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL14539767 | 0.85 | KMT2A (0.51) | KMT2AMEN1ELANEMAPTALDH1A1 | |
| SCHEMBL840978 | 0.85 | LDHB (0.50) | KMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053475-A | Application of surface modified peat catalyst in carbene insertion N-H reaction | 南京工业大学 | 2018-12-21 | — | — | CN | claimed |
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | claimed |
| US-8455646-B2 | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-06-04 | — | — | US | claimed |
| US-20100173880-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-08 | — | — | US | claimed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | claimed |
| EP-4747366-A1 | PROCESS FOR THE REDUCTION OF AROMATIC IMINES WITH NOVEL IMINE REDUCTASES (IREDS) | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| US-20260139283-A1 | PROCESS FOR THE REDUCTION OF AROMATIC IMINES WITH NOVEL IMINE REDUCTASES (IREDS) | HOFFMANN LA ROCHE INC (US) | 2026-05-21 | — | — | US | disclosed |
| WO-2025017089-A1 | PROCESS FOR THE REDUCTION OF AROMATIC IMINES WITH NOVEL IMINE REDUCTASES (IREDS) | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |
| CN-109053475-A | Application of surface modified peat catalyst in carbene insertion N-H reaction | 南京工业大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053475-A | Application of surface modified peat catalyst in carbene insertion N-H reaction | 南京工业大学 | 2018-12-21 | — | — | CN | disclosed |
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | disclosed |
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | disclosed |
| US-8455646-B2 | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-06-04 | — | — | US | disclosed |
| CN-102264734-A | Alkaloid aminoester derivatives and medicinal composition thereof | — | 2011-11-30 | — | — | CN | disclosed |
| EP-2376489-A1 | Alkaloid aminoester derivatives and medicinal composition thereof | Chiesi Farmaceutici S.p.A. (IT) | 2011-10-19 | — | — | EP | disclosed |
| US-20100173880-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-08 | — | — | US | disclosed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | disclosed |
| EP-0028430-B1 | A PROCESS FOR THE ELECTROREDUCTIVE PREPARATION OF ORGANIC COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-01-18 | — | — | EP | disclosed |
| EP-0028430-A1 | A process for the electroreductive preparation of organic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260139283-A1 | PROCESS FOR THE REDUCTION OF AROMATIC IMINES WITH NOVEL IMINE REDUCTASES (IREDS) | CYP2C9, CYP1A1, CYP2E1 | KMT2A 2607/4885MEN1 4398/4885ELANE 4280/4885 |
| US-20100173880-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHRM3, CHRM1, CHRNG | KMT2A 1874/4885MEN1 4121/4885ELANE 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.