Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 5/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 10/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29785504 | 1.00 | PLAT (0.34) | PLATPROKR1HCRTR1HCRTR2PDE10A | |
| SCHEMBL23415004 | 0.90 | SCD5 (0.35) | PLATHCRTR1HCRTR2KDM2BDHODH | |
| SCHEMBL29785433 | 0.90 | SCD5 (0.35) | PLAT | |
| SCHEMBL29785487 | 0.90 | PLAT (0.34) | PLATPROKR1DHODH | |
| SCHEMBL24834779 | 0.90 | PLAT (0.34) | PLATPROKR1DHODH | |
| SCHEMBL24834886 | 0.90 | SCD5 (0.35) | PLAT | |
| SCHEMBL29785492 | 0.89 | PLAT (0.36) | PLATPROKR1PDE10ADHODH | |
| SCHEMBL24834859 | 0.89 | PLAT (0.36) | PLATPROKR1PDE10ADHODH | |
| SCHEMBL24834807 | 0.89 | PROKR1 (0.35) | PLATPROKR1DHODH | |
| SCHEMBL29785462 | 0.89 | PROKR1 (0.35) | PLATPROKR1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114786778-A | Therapeutic compounds | 基因泰克公司 | 2022-07-22 | — | — | CN | claimed |
| US-20230002396-A1 | THERAPEUTIC COMPOUNDS | GENENTECH, INC. (US) | 2023-01-05 | — | — | US | disclosed |
| CN-114786778-A | Therapeutic compounds | 基因泰克公司 | 2022-07-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002396-A1 | THERAPEUTIC COMPOUNDS | YAP1, YES1, TEAD2 | PLAT 3745/4885PROKR1 4095/4885HCRTR1 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.