Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | RARB | P10826 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24835291 | 0.99 | NPSR1 (0.51) | DRD3NPSR1GRIN2BALDH1A1OPRM1 | |
| SCHEMBL24835260 | 0.95 | DRD3 (0.51) | DRD3NPSR1GRIN2BALDH1A1OPRM1 | |
| SCHEMBL24835150 | 0.86 | DRD3 (0.46) | DRD3NPSR1GRIN2BALDH1A1RARB | |
| SCHEMBL24835204 | 0.85 | MEN1 (0.59) | DRD3GRIN2BALDH1A1THRATHRB | |
| SCHEMBL24835290 | 0.83 | MEN1 (0.61) | ALDH1A1L3MBTL1THRATHRBKMT2A | |
| SCHEMBL24835241 | 0.80 | MEN1 (0.54) | DRD3GRIN2BALDH1A1KMT2AMEN1 | |
| SCHEMBL5943779 | 0.80 | MEN1 (0.51) | GRIN2BALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL4692444 | 0.79 | OPRM1 (0.51) | DRD3GRIN2BOPRM1OPRD1OPRK1 | |
| SCHEMBL2355874 | 0.78 | GRIN2B (0.60) | GRIN2BALDH1A1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL9315866 | 0.77 | GRIN2B (0.59) | NPSR1GRIN2BALDH1A1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |