Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30109363 | 0.99 | HSD17B10 (0.48) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL29325329 | 0.84 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30109301 | 0.81 | EP300 (0.45) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL29328207 | 0.79 | MEN1 (0.45) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| Hydrochloric Acid SCHEMBL31056797 | 0.78 | MEN1 (0.44) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL25076804 | 0.78 | ALDH1A1 (0.47) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30109199 | 0.77 | KDM2B (0.43) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30109279 | 0.77 | ALDH1A1 (0.39) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL29328575 | 0.77 | ALDH1A1 (0.44) | HSD17B10KDM4EALDH1A1GAAHPGD | |
| SCHEMBL31248547 | 0.77 | NR1H2 (0.43) | ALDH1A1MEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |