Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30292290 | 0.85 | L3MBTL3 (0.42) | L3MBTL3 | |
| SCHEMBL16409221 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL28325217 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL17782270 | 0.79 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL25076566 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL25620691 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL29148946 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL16409304 | 0.79 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL25076798 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR | |
| SCHEMBL25077023 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043314-A | Benzazepine heteroaromatic ring derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-05-14 | — | — | CN | disclosed |
| WO-2023020566-A1 | BENZO NITROGEN-CONTAINING HETEROAROMATIC RING DERIVATIVE AND USE THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2023-02-23 | — | — | WO | disclosed |