SCHEMBL24835659

SCHEMBL24835659

CC(C)c1nccc2nc(CC(C)c3ncnc4cc[nH]c34)[nH]c12

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.35
PIP4K2C Q8TBX8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19153553 0.81
SCHEMBL14747699 0.78 DYRK1A (0.53) DYRK1APIP4K2C
SCHEMBL21305255 0.72 DDAH1 (0.42)
SCHEMBL18562039 0.65 KDM4E (0.42) DYRK1A
SCHEMBL18237587 0.64 LRRK2 (0.33)
SCHEMBL18237616 0.64 GRM5 (0.38) PIP4K2C
SCHEMBL27010754 0.62 LRRK2 (0.31)
SCHEMBL17320236 0.62 KDR (0.42) DYRK1APIP4K2C
SCHEMBL25549142 0.62 TYK2 (0.36) DYRK1APIP4K2C
SCHEMBL21335020 0.60 MAPK1 (0.38) DYRK1APIP4K2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME BLINKBIO INC (US) 2023-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000993-A1 SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME CD44, MSN, AS3MT DYRK1A 1107/4885PIP4K2C 3184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.