Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272931 | 0.89 | SIGMAR1 (0.54) | LTA4HSIGMAR1ALDH1A1CYP2D6FUCA1 | |
| SCHEMBL3277741 | 0.89 | SIGMAR1 (0.54) | LTA4HSIGMAR1ALDH1A1CYP2D6FUCA1 | |
| SCHEMBL3272922 | 0.89 | SIGMAR1 (0.54) | LTA4HSIGMAR1ALDH1A1CYP2D6FUCA1 | |
| SCHEMBL3274123 | 0.86 | SIGMAR1 (0.53) | LTA4HSIGMAR1ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL3276041 | 0.86 | SIGMAR1 (0.53) | LTA4HSIGMAR1ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL3274127 | 0.86 | SIGMAR1 (0.53) | LTA4HSIGMAR1ALDH1A1CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3278083 | 0.85 | SIGMAR1 (0.51) | LTA4HSIGMAR1ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL31235612 | 0.85 | ACHE (0.49) | LTA4HSIGMAR1GRIN1GRIN2BBCHE | |
| Hydrochloric Acid SCHEMBL3278090 | 0.85 | SIGMAR1 (0.51) | LTA4HSIGMAR1ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL4472074 | 0.82 | BCHE (0.49) | LTA4HSIGMAR1ALDH1A1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |