SCHEMBL248363

SCHEMBL248363

O=C(OO)c1ccccc1Br

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.51
MAPT P10636 4/20 0.51
USP2 O75604 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ALDH1A1 P00352 4/20 0.47
GAA P10253 4/20 0.47
HPGD P15428 3/20 0.47
MIF P14174 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 2/20 0.47
TP53 P04637 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6467406 0.84 KMT2A (0.49) KMT2AMAPTUSP2SMN1; SMN2ALDH1A1
SCHEMBL5484453 0.84 KMT2A (0.49) KMT2AMAPTUSP2SMN1; SMN2ALDH1A1
SCHEMBL29709946 0.83 TSHR (0.52) MAPTALDH1A1HPGDKDM4ELMNA
SCHEMBL6936 0.83 TSHR (0.52) MAPTALDH1A1HPGDKDM4ELMNA
SCHEMBL8860054 0.83 MAPT (0.39) KMT2AMAPTUSP2SMN1; SMN2ALDH1A1
SCHEMBL11816437 0.81 KMT2A (0.64) KMT2AMAPTUSP2SMN1; SMN2ALDH1A1
SCHEMBL11879146 0.80 TSHR (0.50) MAPTALDH1A1HPGDKDM4ELMNA
Water SCHEMBL5320760 0.80 TSHR (0.50) MAPTALDH1A1HPGDKDM4ELMNA
Ammonia Solution, Strong SCHEMBL28928632 0.80 TSHR (0.50) MAPTALDH1A1GAAHPGDKDM4E
SCHEMBL6963405 0.80 KMT2A (0.46) KMT2AMAPTUSP2SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2588502-B1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION NOURYON CHEMICALS INT BV (NL) 2021-03-31 EP disclosed
US-8987391-B2 Polymerization process with in-situ initiator formation AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-03-24 US disclosed
US-20130211019-A1 Polymerization Process with In-Situ Initiator Formation AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2013-08-15 US disclosed
EP-2588502-A1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION Akzo Nobel Chemicals International B.V. (NL) 2013-05-08 EP disclosed
WO-2012000916-A1 POLYMERIZATION PROCESS WITH IN-SITU INITIATOR FORMATION AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2012-01-05 WO disclosed
EP-0322639-A1 (22R,23R,24S)-22,23-Epoxy-2 alpha, 3 alpha-isopropylidenedioxy-B-homo-7-oxa-5 alpha-stigmastan-6-one, process for preparation thereof and plant growth regulating composition containing the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-07-05 EP disclosed
US-4008175-A Organic acid anhydride-peroxydicarbonate composition PPG INDUSTRIES, INC. (US) 1977-02-15 US disclosed
US-3985720-A Polymerization of ethylenically unsaturated monomer employing a catalyst system comprising dialkylpyrocarbonate, organic acid anhydride, alkaline reagent and H2 O2 PPG INDUSTRIES, INC. (US) 1976-10-12 US disclosed
US-3978032-A ALKALINE BUFFER, ANHYDRIDE, PERACID, ALKYL HALOFORMATE PPG INDUSTRIES, INC. (US) 1976-08-31 US disclosed