Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467406 | 0.82 | KMT2A (0.49) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL5484453 | 0.82 | KMT2A (0.49) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL248363 | 0.80 | KMT2A (0.51) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL10436464 | 0.78 | MIF (0.50) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL29433258 | 0.78 | TSHR (0.61) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL23659 | 0.78 | TSHR (0.61) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL8923280 | 0.78 | CASP3 (0.49) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL25167793 | 0.77 | KMT2A (0.49) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL5956543 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL10368435 | 0.76 | LMNA (0.63) | KMT2AMAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070622-B1 | DERIVATIVES OF M.139,603 USEFUL AS GROWTH PROMOTORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-14 | — | — | EP | claimed |
| EP-0070622-A1 | Derivatives of M.139,603 useful as growth promotors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-01-26 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0316163-B1 | TETRONASIN OR DERIVATIVES THEREOF FOR VETERINARY TREATMENT | PITMAN-MOORE LIMITED (GB) | 1993-03-31 | — | — | EP | disclosed |
| US-4999374-A | Treatment of swine dysentery, antibiotic tetronasin | COOPER ANIMAL HEALTH LIMITED (GB) | 1991-03-12 | — | — | US | disclosed |
| EP-0316163-A2 | Tetronasin or derivatives thereof for veterinary treatment | PITMAN-MOORE LIMITED (GB) | 1989-05-17 | — | — | EP | disclosed |
| EP-0070622-B1 | DERIVATIVES OF M.139,603 USEFUL AS GROWTH PROMOTORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-01-14 | — | — | EP | disclosed |
| US-4443471-A | Derivatives of M.139,603 useful as growth promoters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-04-17 | — | — | US | disclosed |
| EP-0070622-A1 | Derivatives of M.139,603 useful as growth promotors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-01-26 | — | — | EP | disclosed |