SCHEMBL5484453

SCHEMBL5484453

O=C(OC(=O)c1ccccc1Br)c1ccccc1Br

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
MAPT P10636 4/20 0.49
ALDH1A1 P00352 4/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 3/20 0.49
GAA P10253 2/20 0.49
USP2 O75604 1/20 0.49
MIF P14174 1/20 0.49
POLB P06746 1/20 0.49
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484457 0.90 KMT2A (0.49) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL25167793 0.89 KMT2A (0.49) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL11658581 0.88 CES2 (0.50) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL6467406 0.86 KMT2A (0.49) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL8923280 0.86 CASP3 (0.49) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL248363 0.84 KMT2A (0.51) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL8674787 0.82 ALDH1A1 (0.54) KMT2AMAPTALDH1A1GAARAB9A
SCHEMBL23659 0.82 TSHR (0.61) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL29433258 0.82 TSHR (0.61) KMT2AMAPTALDH1A1HPGDKDM4E
SCHEMBL6963405 0.82 KMT2A (0.46) KMT2AMAPTALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111154083-B Phthalic anhydride polyester polyol with narrow molecular weight distribution and preparation method thereof 万华化学集团股份有限公司 2022-04-22 CN claimed
CN-111286083-A Bromine flame retardant and preparation method thereof 广州埃登达化工有限公司 2020-06-16 CN claimed
CN-111154083-A Phthalic anhydride polyester polyol with narrow molecular weight distribution and preparation method thereof 万华化学集团股份有限公司 2020-05-15 CN claimed
US-20180273819-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS COMPRISING TRIAMINES AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS LLC (US) 2018-09-27 US claimed
WO-2016179028-A1 THERMAL ENERGY STORAGE PHASE AND TEMPERATURE STABILIZATION CHANGE MATERIALS AND METHODS FOR MAKING AND USING THEM ENTROPY SOLUTIONS, LLC. (US) 2016-11-10 WO claimed
US-7247740-B2 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2007-07-24 US claimed
EP-1472217-B1 METHOD FOR PRODUCING PERFLUOROALKANE SULFONIC ACID ESTERS AND THE SALTS THEREOF MERCK PATENT GMBH (DE) 2007-01-24 EP claimed
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2005-04-21 US claimed
WO-2025015175-A2 HEATING, VENTILATION, AND AIR CONDITIONING (HVAC) SYSTEMS AND METHODS FOR USING SAME STASIS ENERGY GROUP, LLC (US) 2025-01-16 WO disclosed
CN-115894415-A Synthesis method of dianhydride monomer 慧迈材料科技(广东)有限公司 2023-04-04 CN disclosed
CN-115485269-A Ring-closure synthesis of macrocyclic MCL-1 inhibitor intermediates 安进公司 2022-12-16 CN disclosed
CN-111154083-B Phthalic anhydride polyester polyol with narrow molecular weight distribution and preparation method thereof 万华化学集团股份有限公司 2022-04-22 CN disclosed
CN-111286083-A Bromine flame retardant and preparation method thereof 广州埃登达化工有限公司 2020-06-16 CN disclosed
CN-111286083-A Bromine flame retardant and preparation method thereof 广州埃登达化工有限公司 2020-06-16 CN disclosed
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid MERCK PATENT GMBH (DE) 2005-04-21 US disclosed
US-6297372-B1 NITRATION OF THE N-ACYL DERIVATIVES ASAHI KASEI KABUSHIKI KAISHA (JP) 2001-10-02 US disclosed
EP-0919556-A1 PROCESS FOR THE PREPARATION OF HEXANITROHEXAAZAISOWURTZITANES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1999-06-02 EP disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed
US-3970671-A XANTHENE, PRESSURE SENSITIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1976-07-20 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085655-A1 Reacting perfluoroalkanesulfonic acid directly with dialkyl carbonate to give alkyl perfluoroalkanesulfonate optionally in the presence of a water or alcohol consuming reagent, and preparing an alkyl perfluoroalkanesulfonate with an alkylamine or alkylphosphine to prepare perfluoroalkanesulfonic acid PFKFB2, PFKFB3, PHOSPHO1 KMT2A 2984/4885MAPT 4553/4885ALDH1A1 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.