Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25165002 | 0.78 | — | — | |
| SCHEMBL14413861 | 0.76 | CYP2D6 (0.36) | USP2NPSR1 | |
| SCHEMBL24837477 | 0.76 | USP2 (0.36) | USP2NPSR1 | |
| SCHEMBL23268386 | 0.75 | USP2 (0.35) | USP2 | |
| SCHEMBL13798801 | 0.74 | ROCK2 (0.31) | — | |
| SCHEMBL11245376 | 0.73 | — | — | |
| SCHEMBL10515290 | 0.72 | USP2 (0.37) | USP2 | |
| SCHEMBL10163094 | 0.71 | ALDH1A1 (0.48) | USP2ALDH1A1NPSR1 | |
| SCHEMBL11253304 | 0.71 | ALDH1A1 (0.46) | USP2ALDH1A1 | |
| SCHEMBL11371451 | 0.71 | ALDH1A1 (0.46) | USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022250170-A9 | SMALL MOLECULE INHIBITORS OF KRAS MUTATED PROTEINS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2023-01-05 | — | — | WO | disclosed |