Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 3/20 | 0.94 |
| ▸ | LMNA | P02545 | 3/20 | 0.94 |
| ▸ | TP53 | P04637 | 3/20 | 0.94 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.94 |
| ▸ | THRB | P10828 | 1/20 | 0.94 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | ATP1A1 | P05023 | 12/20 | 0.67 |
| ▸ | ATP1B1 | P05026 | 12/20 | 0.67 |
| ▸ | ATP1A2 | P50993 | 12/20 | 0.67 |
| ▸ | ATP1B2 | P14415 | 11/20 | 0.67 |
| ▸ | ATP1B3 | P54709 | 11/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.67 |
| ▸ | STAT3 | P40763 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | RORC | P51449 | 1/20 | 0.67 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.67 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20251039 | 1.00 | PAX8 (0.94) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL18947801 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL18277653 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL18364709 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL23054706 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL44110 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL18223891 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL15959375 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| Lanatoside C SCHEMBL20582682 | 0.97 | PAX8 (1.00) | PAX8LMNATP53SMN1; SMN2THRB | |
| SCHEMBL18949552 | 0.94 | PAX8 (0.94) | PAX8LMNATP53SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000881-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000881-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF HEARING LOSS | CDK2, CDK5, CDK20 | PAX8 2734/4885LMNA 183/4885TP53 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.