SCHEMBL248380

SCHEMBL248380

C=C(C)C(=O)OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)COC(=O)C(=C)C

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.41
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL246347 1.00 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL248332 1.00 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL248056 1.00 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL246497 1.00 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL247163 1.00 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL246414 0.98 TSHR (0.45) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1536958 0.94 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL632209 0.94 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL36922 0.94 TSHR (0.40) TSHRTHRBALDH1A1
SCHEMBL20994101 0.94 TSHR (0.40) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12625134-B2 Complex liquid crystal droplets MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-05-12 US disclosed
US-12274993-B2 Systems and methods for affecting interactions of electromagnetic radiation with janus droplets for sensitive detection of species MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-04-15 US disclosed
US-20250102716-A1 ARTICLES AND METHODS FOR GENERATING TUNABLE COLORATION AND INTERFERENCE UPON REFLECTION OF INCIDENT ELECTROMAGNETIC RADIATION THE PENN STATE RESEARCH FOUNDATION 2025-03-27 US disclosed
US-20240272077-A1 ARTICLES AND METHODS FOR GENERATION OF TUNABLE COLORATION AND INTERFERENCE PENN STATE RES FOUND (US) 2024-08-15 US disclosed
US-12061194-B2 Systems including Janus droplets with binding moieties for a virus, a pathogen or a bacterium MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-08-13 US disclosed
US-11953439-B2 Articles and methods for generation of tunable coloration and interference MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-04-09 US disclosed
US-20230185003-A1 SUBSTRATES THAT EXHIBIT INTERFERENCE PATTERNS UPON THE REFLECTION OF INCIDENT ELECTROMAGNETIC RADIATION AND METHODS OF MAKING AND USING THEREOF NATIONAL SCIENCE FOUNDATION 2023-06-15 US disclosed
US-11654404-B2 Light emitting droplets and related methods MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-05-23 US disclosed
US-11630389-B2 Curable composition for imprinting, replica mold and its production process AGC Inc. (JP) 2023-04-18 US disclosed
US-20220205989-A1 SYSTEMS INCLUDING JANUS DROPLETS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-06-30 US disclosed
US-20120270021-A1 METHOD FOR PRODUCING ANTIREFLECTION FILM, ANTIREFLECTION FILM, AND COATING COMPOSITION FUJIFILM CORPORATION (JP) 2012-10-25 US disclosed
US-20120207992-A1 PRODUCTION METHOD OF ANTIREFLECTION FILM, ANTIREFLECTION FILM AND COATING COMPOSITION FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120207990-A1 PRODUCTION METHOD OF ANTIREFLECTION FILM, ANTIREFLECTION FILM AND COATING COMPOSITION FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20120003467-A1 Antistatic laminate, optical film, polarizing plate, image display device and production method of antistatic laminate FUJI FILM CORPORATION (JP) 2012-01-05 US disclosed
US-20110026121-A1 Laminate, antireflective film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20110026126-A1 Antireflection film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-02-03 US disclosed
US-20090148706-A1 OPTICAL WAVEGUIDE HAVING PERFLUOROADAMANTANE STRUCTURE OMRON CORPORATION (JP) 2009-06-11 US disclosed
EP-2015113-A1 OPTICAL WAVEGUIDE HAVING PERFLUOROADAMANTANE STRUCTURE Omron Corporation (JP) 2009-01-14 EP disclosed
US-20070041697-A1 Optical component OMRON CORPORATION (JP) 2007-02-22 US disclosed
EP-1693389-A1 OPTICAL COMPONENT Omron Corporation (JP) 2006-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625134-B2 Complex liquid crystal droplets MAFG, SFN, FLNB TSHR 2676/4885THRB 3273/4885ALDH1A1 4423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.