MAFG — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL16085609	1.00	1/20
SCHEMBL29419037	1.00	1/20
SCHEMBL30440736	1.00	1/20
SCHEMBL16085530	0.92	1/20
SCHEMBL16085439	0.88	1/20
SCHEMBL16085434	0.87	1/20
SCHEMBL16085453	0.87	1/20
SCHEMBL16085466	0.85	1/20
SCHEMBL16085431	0.84	1/20
SCHEMBL16085413	0.84	1/20
SCHEMBL16085432	0.83	1/20
SCHEMBL16085145	0.83	1/20
SCHEMBL16085467	0.83	1/20
SCHEMBL16085599	0.82	1/20
SCHEMBL16085449	0.81	1/20
SCHEMBL16085502	0.81	1/20
SCHEMBL16085535	0.81	1/20
SCHEMBL16085433	0.80	1/20
SCHEMBL16085468	0.80	1/20
SCHEMBL16085534	0.79	1/20

Clinical trials — most relevant to MAFG by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Adding Exenatide to Insulin Therapy for Patients With Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease	PHASE4	COMPLETED
Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients	PHASE4	UNKNOWN
Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.	PHASE3	COMPLETED
Efficacy and Safety of Oral Immunotherapy With GcMAF in Hospitalized Patients With COVID-19 Pneumonia	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Effect of CoQ10 on the Outcome of MAFLD Patients	PHASE2	RECRUITING
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes	nan	COMPLETED
Calorie Restriction in Multiple Sclerosis	nan	ACTIVE_NOT_RECRUITING
Nutrition Education and Quality of Life in Cancer Cachexia	nan	UNKNOWN
Recall of a Cohort of Subjects in the Mediterranean Area. Monitoring of Liver Diseases (NUTRIHEP 3).	nan	NOT_YET_RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Nasturtium (Tropaeolum Majus L) Intake and Biochemical Parameters in Pre-diabetic Subjects in Bogota Colombia	nan	COMPLETED
RORC Genetic Polymorphism of Rheumatoid Arthritis	nan	COMPLETED
for Adipose Tissue DIabetes VAriants (fATDIVA)	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.	nan	COMPLETED
Growth Hormone Feedback to Insulin-like Growth Factor-I (IGF-1) and Oral Glucose Tolerance Test (OGTT)	nan	COMPLETED
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients	nan	UNKNOWN
Influence of Dietary Fiber-rich Meals on Gene Expression and Postprandial Glucose and Lipid Response	nan	COMPLETED
COPENHAGEN Minipuberty Study	nan	UNKNOWN
CAP Fetge Gras. Lifestyle Modification Program in Catalonia.	nan	COMPLETED
Clinical Study of Desuzumab in the Treatment of Knee Osteoarthritis	nan	RECRUITING
A Pilot Study of Berberine (Soloways ™) in Patients with Type 2 Diabetes Mellitus Carrying TCF7L2 Polymorphisms	nan	COMPLETED
Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise	nan	COMPLETED
The Effects of HER2 Receptor Signaling on Human Brown Fat Activity	nan	RECRUITING
Understanding Immunotherapy Resistance Mechanisms in Advanced Melanoma	nan	COMPLETED
Genetic Background of Patients With Low Von Willebrand Factor Levels	nan	COMPLETED
Semaglutide Effectiveness in Patients With Metabolic Dysfunction-Associated Fatty Liver Disease in the Real World Practice	nan	ACTIVE_NOT_RECRUITING
Effects of Gallotannins on the Gut Microbiome and How it Affects Inflammatory Markers Among Obese Individuals.	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MAFG binder may also engage these)

Protein	Name	Similarity
O54790	—	1.000	O54790 →
A5PJV0	—	1.000	A5PJV0 →
MAFK	Transcription factor MafK	1.000	landscape →
Q90889	—	1.000	Q90889 →
Q90595	—	1.000	Q90595 →
Q76MX4	—	0.999	Q76MX4 →
Q61827	—	0.999	Q61827 →
Q90596	—	0.995	Q90596 →
A7YY73	—	0.995	A7YY73 →
O54791	—	0.993	O54791 →
Q9ULX9	—	0.992	Q9ULX9 →
O57337	—	0.987	O57337 →
Q04666	—	0.986	Q04666 →
Q3ZBG4	—	0.986	Q3ZBG4 →
P35428	—	0.986	P35428 →
F1QW76	—	0.985	F1QW76 →
Q90VV1	—	0.985	Q90VV1 →
Q6IRB2	—	0.984	Q6IRB2 →
Q01071	—	0.984	Q01071 →
SMARCC2	SWI/SNF complex subunit SMARCC2	0.984	landscape →
Q5PPM5	—	0.984	Q5PPM5 →
Q01070	—	0.983	Q01070 →
Q90Z12	—	0.983	Q90Z12 →
Q7Z3E5	—	0.983	Q7Z3E5 →
Q8BHR2	—	0.983	Q8BHR2 →
O95475	—	0.983	O95475 →
P13097	—	0.983	P13097 →
Q8TC92	—	0.983	Q8TC92 →
SMARCC1	SWI/SNF complex subunit SMARCC1	0.982	landscape →
Q28E45	—	0.982	Q28E45 →