SCHEMBL2483852

SCHEMBL2483852

CC(O)(O)Oc1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 8/20 0.64
ESR1 P03372 8/20 0.64
HPGD P15428 3/20 0.64
TSHR P16473 3/20 0.64
CYP3A4 P08684 2/20 0.64
AR P10275 1/20 0.64
SLC6A2 P23975 1/20 0.64
SLC6A4 P31645 1/20 0.64
HTR6 P50406 1/20 0.64
ESRRG P62508 1/20 0.64
SLC6A3 Q01959 1/20 0.64
HSD17B10 Q99714 1/20 0.64
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
SHBG P04278 1/20 0.39
LTA4H P09960 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7062451 0.92 ESR1 (0.48) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL26910 0.89 MEN1 (0.55) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL12204980 0.86 ESR2 (0.67) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL24487 0.86 ESR2 (0.67) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL28498001 0.84 ALDH1A1 (0.55) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL7937266 0.82 ESR2 (0.61) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL7929165 0.82 ESR1 (0.61) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL7773689 0.82 ESR1 (0.55) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL4450783 0.81 ESR1 (0.73) ESR2ESR1HPGDTSHRCYP3A4
SCHEMBL10865719 0.81 ESR1 (0.73) ESR2ESR1HPGDTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111333814-A Thermoplastic polyurethane, preparation method and application thereof 万华化学集团股份有限公司 2020-06-26 CN claimed
US-4387139-A Elastomeric, ethylenically unsaturated polyurethanes and radiation polymerizable mixtures containing such polyurethanes KALLE, NIEDERLASSUNG DER HOECHST AG (DE) 1983-06-07 US claimed
CN-111333814-B Thermoplastic polyurethane, preparation method and application thereof 万华化学集团股份有限公司 2022-01-07 CN disclosed
CN-111333814-A Thermoplastic polyurethane, preparation method and application thereof 万华化学集团股份有限公司 2020-06-26 CN disclosed
EP-2746357-B1 Layered material comprising polyester resin 3M INNOVATIVE PROPERTIES CO (US) 2018-05-30 EP disclosed
EP-2376585-B1 LAYERED MATERIAL CONTAINING POLYVINYL BUTYRAL 3M INNOVATIVE PROPERTIES CO (US) 2017-07-26 EP disclosed
EP-2934794-A1 DUAL FUNCTIONAL LAYERED MATERIAL 3M Innovative Properties Company (US) 2015-10-28 EP disclosed
WO-2014099731-A1 DUAL FUNCTIONAL LAYERED MATERIAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-06-26 WO disclosed
EP-2746357-A1 Layered material comprising polyester resin 3M Innovative Properties Company (US) 2014-06-25 EP disclosed
EP-2746043-A1 Dual Functional Layered Material 3M Innovative Properties Company (US) 2014-06-25 EP disclosed
US-20110256391-A1 LAYERED MATERIAL CONTAINING POLYVINYL BUTYRAL 3M INNOVATIVE PROPERTIES COMPANY 2011-10-20 US disclosed
EP-0435402-A2 Resin composition based on a polyester resin, an amino resin and an epoxy resin DSM N.V. (NL) 1991-07-03 EP disclosed
EP-0418733-A2 Radiation-curable composition and method of producing a solder mask MORTON INTERNATIONAL, INC. (US) 1991-03-27 EP disclosed
EP-0048913-B1 RADIATION-POLYMERIZABLE MIXTURE CONTAINING RUBBER-ELASTIC ETHYLENICALLY UNSATURATED POLYURETHANES HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-29 EP disclosed
EP-0063304-B1 COMPOSITION POLYMERISABLE BY RADIATION, AND PHOTOPOLYMERISABLE COPYING MATERIAL MADE THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1985-09-18 EP disclosed
US-4399239-A MOLDING COMPOSITION OR FOAM HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-16 US disclosed
US-4387139-A Elastomeric, ethylenically unsaturated polyurethanes and radiation polymerizable mixtures containing such polyurethanes KALLE, NIEDERLASSUNG DER HOECHST AG (DE) 1983-06-07 US disclosed
EP-0063304-A2 Composition polymerisable by radiation, and photopolymerisable copying material made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-27 EP disclosed
EP-0048913-A1 Radiation-polymerizable mixture containing rubber-elastic ethylenically unsaturated polyurethanes HOECHST AKTIENGESELLSCHAFT (DE) 1982-04-07 EP disclosed
US-4283520-A USING A CYANOACETYL CURING AGENT AND A PHENYLUREA ACCELERATOR CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed