Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.33 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.33 |
| ▸ | RPS17 | P08708 | 1/20 | 0.33 |
| ▸ | RPSA | P08865 | 1/20 | 0.33 |
| ▸ | RPS2 | P15880 | 1/20 | 0.33 |
| ▸ | RPL35A | P18077 | 1/20 | 0.33 |
| ▸ | RPL7 | P18124 | 1/20 | 0.33 |
| ▸ | RPL17 | P18621 | 1/20 | 0.33 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.33 |
| ▸ | RPS3 | P23396 | 1/20 | 0.33 |
| ▸ | RPS12 | P25398 | 1/20 | 0.33 |
| ▸ | RPL13 | P26373 | 1/20 | 0.33 |
| ▸ | RPL10 | P27635 | 1/20 | 0.33 |
| ▸ | RPL12 | P30050 | 1/20 | 0.33 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.33 |
| ▸ | RPL22 | P35268 | 1/20 | 0.33 |
| ▸ | RPL4 | P36578 | 1/20 | 0.33 |
| ▸ | RPS19 | P39019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483956 | 0.87 | PLA2G7 (0.31) | — | |
| SCHEMBL2481064 | 0.84 | PLA2G7 (0.33) | — | |
| SCHEMBL3250338 | 0.82 | — | — | |
| SCHEMBL414720 | 0.81 | RPLP1 (0.44) | MAPTSMN1; SMN2RPLP1RPLP0RPS17 | |
| SCHEMBL411690 | 0.80 | ALDH1A1 (0.46) | MAPTSMN1; SMN2RPLP1RPLP0RPS17 | |
| SCHEMBL417286 | 0.80 | SMN1; SMN2 (0.40) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL415251 | 0.78 | ALDH1A1 (0.42) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL3252038 | 0.73 | ALDH1A1 (0.31) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2486849 | 0.72 | TP53 (0.32) | MAPTSMN1; SMN2RPLP1RPLP0RPS17 | |
| SCHEMBL416131 | 0.72 | CNR2 (0.35) | MAPTRPLP1RPLP0RPS17RPSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376431-A1 | NOVEL SUBSTITUTED ARYL DERIVATIVES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES AS ANTI-HIV AGENTS | LABORATOIRE BIODIM (FR) | 2011-10-19 | — | — | EP | disclosed |