Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22527107 | 0.81 | ALOX15 (0.34) | ANPEPENPEPALOX15BLMPMP22 | |
| SCHEMBL8915536 | 0.81 | ANPEP (0.64) | ANPEPENPEP | |
| SCHEMBL16710256 | 0.81 | ANPEP (0.44) | ANPEPENPEPALOX15BLMPMP22 | |
| SCHEMBL20342061 | 0.78 | ANPEP (0.41) | ANPEPENPEPALOX15BLMPMP22 | |
| SCHEMBL10065458 | 0.78 | ANPEP (0.50) | ANPEPENPEPALOX15BLMPMP22 | |
| SCHEMBL24712877 | 0.78 | ANPEP (0.41) | ANPEPENPEPALOX15BLMPMP22 | |
| SCHEMBL8975958 | 0.78 | ENPEP (0.55) | ANPEPENPEPALOX15BLMPMP22 | |
| SCHEMBL16350175 | 0.75 | ANPEP (0.43) | ANPEPENPEPALOX15BLMPMP22 | |
| SCHEMBL14002565 | 0.72 | DPP4 (0.42) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL25662387 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002788-A1 | AAV3B VARIANTS WITH IMPROVED PRODUCTION YIELD AND LIVER TROPISM | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2023-01-05 | — | — | US | disclosed |