Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.57 |
| ▸ | CCNK | O75909 | 5/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.57 |
| ▸ | CDK9 | P50750 | 5/20 | 0.57 |
| ▸ | CDK12 | Q9NYV4 | 5/20 | 0.57 |
| ▸ | FLT3 | P36888 | 5/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.38 |
| ▸ | GSK3A | P49840 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 5/20 | 0.38 |
| ▸ | CCNH | P51946 | 5/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.38 |
| ▸ | CLK1 | P49759 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967204 | 0.79 | CDK2 (0.51) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL20846287 | 0.76 | CDK2 (0.48) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL24839369 | 0.74 | CDK7 (0.55) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL25603525 | 0.74 | CCNK (0.56) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL22963813 | 0.74 | GSK3A (0.41) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL20839192 | 0.74 | CAMKK2 (0.45) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL9941759 | 0.73 | CDK2 (0.42) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL25603527 | 0.73 | CCNK (1.00) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL20561594 | 0.73 | CCNT1 (0.44) | CDK2CCNT1CCNKCCNE1CDK9 | |
| SCHEMBL20561824 | 0.72 | CCNT1 (0.44) | CDK2CCNT1CCNKCCNE1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000870-A1 | METHODS OF TREATING CANCER IN BIOMARKER-IDENTIFIED PATIENTS WITH INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000870-A1 | METHODS OF TREATING CANCER IN BIOMARKER-IDENTIFIED PATIENTS WITH INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, RB1, MKI67 | CDK2 20/4885CCNT1 41/4885CCNK 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.