Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.51 |
| ▸ | IL1B | P01584 | 10/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24840029 | 1.00 | NLRP3 (0.51) | NLRP3IL1BPOLBMAPK1NPSR1 | |
| SCHEMBL30108706 | 1.00 | NLRP3 (0.51) | NLRP3IL1BPOLBMAPK1NPSR1 | |
| SCHEMBL28934320 | 0.87 | NLRP3 (0.41) | NLRP3IL1BMAPK1 | |
| SCHEMBL28934321 | 0.87 | NLRP3 (0.41) | NLRP3IL1BMAPK1 | |
| SCHEMBL26772312 | 0.82 | NLRP3 (0.51) | NLRP3IL1B | |
| SCHEMBL30108895 | 0.81 | CHEK2 (0.45) | NLRP3IL1B | |
| SCHEMBL28934840 | 0.81 | CHEK2 (0.45) | NLRP3IL1B | |
| SCHEMBL28934843 | 0.81 | CHEK2 (0.45) | NLRP3IL1B | |
| SCHEMBL24840287 | 0.79 | NLRP3 (0.52) | NLRP3IL1B | |
| SCHEMBL28934400 | 0.79 | NLRP3 (0.52) | NLRP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881401-A | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023278438-A1 | NLRP3 MODULATORS | ZOMAGEN BIOSCIENCES LTD (US) | 2023-01-05 | — | — | WO | disclosed |
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |