⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230990 | 0.86 | — | — | |
| SCHEMBL22064182 | 0.85 | CYP2D6 (0.31) | — | |
| SCHEMBL600356 | 0.85 | CYP2D6 (0.31) | — | |
| SCHEMBL17534905 | 0.79 | — | — | |
| SCHEMBL19019151 | 0.70 | CYP2D6 (0.33) | — | |
| SCHEMBL13446176 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL17391144 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL3902389 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL12073473 | 0.66 | — | — | |
| SCHEMBL18700017 | 0.66 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376447-B1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID PHARMA LTD (IN) | 2017-08-09 | — | — | EP | claimed |
| US-8466145-B2 | Dipeptidyl peptidase IV inhibitors | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2013-06-18 | — | — | US | claimed |
| US-20110257164-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-10-20 | — | — | US | claimed |
| EP-2376447-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | Orchid Research Laboratories Limited (IN) | 2011-10-19 | — | — | EP | claimed |
| WO-2010079413-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-07-15 | — | — | WO | claimed |
| EP-2376447-B1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID PHARMA LTD (IN) | 2017-08-09 | — | — | EP | disclosed |
| US-8466145-B2 | Dipeptidyl peptidase IV inhibitors | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2013-06-18 | — | — | US | disclosed |
| US-20110257164-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-10-20 | — | — | US | disclosed |
| EP-2376447-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | Orchid Research Laboratories Limited (IN) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010079413-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-07-15 | — | — | WO | disclosed |