SCHEMBL18700017

SCHEMBL18700017

O=C1OC(=O)C2CCC3CC(CCC1C2)C(=O)OC3=O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
GMNN O75496 1/20 0.42
PPM1B O75688 1/20 0.42
LMNA P02545 1/20 0.42
PPP1CC P36873 1/20 0.42
TFPI2 P48307 1/20 0.42
RAB9A P51151 1/20 0.42
PPP5C P53041 1/20 0.42
PPP1CA P62136 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
NFKB1 P19838 1/20 0.42
THPO P40225 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709834 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL3721811 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20428057 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL18700218 0.97 KDM4E (0.40) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20041250 0.94 KDM4E (0.39) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20646727 0.92 KDM4E (0.37) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL18700046 0.89 KDM4E (0.36) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL23895076 0.88 KDM4E (0.39) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL62433 0.88 KDM4E (0.39) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL3764057 0.88 KDM4E (0.39) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190292138-A1 DIAMINE COMPOUND AND METHOD FOR PRODUCING SAME LG CHEM, LTD. (KR) 2019-09-26 US disclosed
US-20170343864-A1 Liquid Crystal Display Device and Method of Manufacturing the Same LG DISPLAY CO., LTD. (KR) 2017-11-30 US disclosed
US-9766501-B2 Liquid crystal display device and method of manufacturing the same LG DISPLAY CO., LTD. (KR) 2017-09-19 US disclosed
US-9611358-B2 Laminate, and element comprising substrate manufactured using same LG CHEM, LTD. (KR) 2017-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292138-A1 DIAMINE COMPOUND AND METHOD FOR PRODUCING SAME DDC, CAD, AOC1 KDM4E 2020/4885GMNN 1818/4885PPM1B 2468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.