Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606738 | 0.81 | MAPT (0.47) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1855812 | 0.79 | SRD5A1 (0.42) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL29854633 | 0.79 | SRD5A1 (0.42) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1855814 | 0.79 | SRD5A1 (0.42) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL2688156 | 0.78 | MAPT (0.38) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1857232 | 0.78 | MAPT (0.38) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL1857233 | 0.78 | MAPT (0.38) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL18608901 | 0.77 | MAPT (0.39) | MAPTRAB9ANPC1NFKB1NFKB2 | |
| SCHEMBL15340735 | 0.77 | MAPT (0.40) | MAPTNPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL24844 | 0.76 | ALDH1A1 (0.39) | MAPTRAB9ANPC1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |