SCHEMBL24842014

SCHEMBL24842014

COC(=O)c1cnn(CCNCCO)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 1/20 0.39
GRM2 Q14416 1/20 0.38
IGF1R P08069 1/20 0.35
POLB P06746 1/20 0.35
CYP4A11 Q02928 3/20 0.35
SLC40A1 Q9NP59 2/20 0.35
ACHE P22303 2/20 0.35
HEXA P06865 1/20 0.34
HEXB P07686 1/20 0.34
CYP4F2 P78329 2/20 0.34
AGTR1 P30556 1/20 0.33
AGTR2 P50052 1/20 0.33
GLA P06280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30163168 0.86 L3MBTL1 (0.40) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL30162871 0.82 L3MBTL1 (0.43) L3MBTL1IGF1RSLC40A1ACHE
SCHEMBL24842016 0.81 L3MBTL1 (0.45) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL20541050 0.80 L3MBTL1 (0.44) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL2187671 0.80 L3MBTL1 (0.45) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL24828550 0.79 L3MBTL1 (0.49) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL22064000 0.79 L3MBTL1 (0.49) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL27645962 0.78 L3MBTL1 (0.55) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL27175170 0.77 L3MBTL1 (0.46) L3MBTL1ALDH1A1KDM4EHPGDGRM2
SCHEMBL29219186 0.75 L3MBTL1 (0.45) L3MBTL1ALDH1A1KDM4EHPGDGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277517-A1 ACYCLIC NUCLEIC ACID MIMIC COMPRISING PENTACYCLIC BASE 동아대학교 산학협력단 2023-01-05 WO disclosed
WO-2023277517-A1 ACYCLIC NUCLEIC ACID MIMIC COMPRISING PENTACYCLIC BASE 동아대학교 산학협력단 2023-01-05 WO disclosed