SCHEMBL30162871

SCHEMBL30162871

NC(=O)c1cnn(CCNCCO)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
SLC40A1 Q9NP59 6/20 0.36
JAK3 P52333 1/20 0.36
NAMPT P43490 1/20 0.35
ACHE P22303 2/20 0.33
MKNK1 Q9BUB5 1/20 0.33
MKNK2 Q9HBH9 1/20 0.33
IGF1R P08069 1/20 0.33
HAT1 O14929 1/20 0.33
EP300 Q09472 1/20 0.33
PAICS P22234 1/20 0.33
CFD P00746 1/20 0.33
KLKB1 P03952 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
TERT O14746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22048432 0.84 L3MBTL1 (0.50) L3MBTL1JAK3NAMPTACHEMKNK1
SCHEMBL24842014 0.82 L3MBTL1 (0.44) L3MBTL1SLC40A1ACHEIGF1R
SCHEMBL24842015 0.78 L3MBTL1 (0.45) L3MBTL1JAK3NAMPTACHEMKNK1
SCHEMBL18281316 0.77 L3MBTL1 (0.44) L3MBTL1ACHEMKNK1MKNK2CFD
SCHEMBL13417602 0.76 L3MBTL1 (0.58) L3MBTL1SLC40A1PAICSKLKB1
SCHEMBL24841255 0.76 JAK3 (0.47) L3MBTL1JAK3NAMPTACHEMKNK1
SCHEMBL30636822 0.76 L3MBTL1 (0.49) L3MBTL1ACHEMKNK1MKNK2CFD
SCHEMBL2701041 0.76 L3MBTL1 (0.72) L3MBTL1JAK3NAMPTACHEMKNK1
SCHEMBL27815356 0.73 L3MBTL1 (0.58) L3MBTL1JAK3NAMPTACHEMKNK1
SCHEMBL18792401 0.73 SLC40A1 (0.68) SLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277517-A1 ACYCLIC NUCLEIC ACID MIMIC COMPRISING PENTACYCLIC BASE 동아대학교 산학협력단 2023-01-05 WO claimed
WO-2023277517-A1 ACYCLIC NUCLEIC ACID MIMIC COMPRISING PENTACYCLIC BASE 동아대학교 산학협력단 2023-01-05 WO disclosed