SCHEMBL24842015

SCHEMBL24842015

NC(=O)c1cnn(CCCCCCO)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.45
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
JAK2 O60674 5/20 0.36
JAK1 P23458 2/20 0.36
JAK3 P52333 2/20 0.36
ACHE P22303 2/20 0.35
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35
TLR8 Q9NR97 1/20 0.35
NAMPT P43490 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
HDAC1 Q13547 4/20 0.33
HDAC6 Q9UBN7 4/20 0.33
GBA1 P04062 2/20 0.33
HDAC3 O15379 1/20 0.33
TYK2 P29597 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22048432 0.86 L3MBTL1 (0.50) L3MBTL1JAK2JAK1JAK3ACHE
SCHEMBL21942690 0.86 L3MBTL1 (0.55) L3MBTL1JAK1JAK3TLR8
SCHEMBL18321196 0.84 L3MBTL1 (0.57) L3MBTL1JAK2JAK1JAK3ACHE
SCHEMBL27815356 0.82 L3MBTL1 (0.58) L3MBTL1JAK2JAK1JAK3ACHE
SCHEMBL24842024 0.81 L3MBTL1 (0.43) L3MBTL1JAK2JAK1JAK3ACHE
SCHEMBL24842016 0.80 L3MBTL1 (0.45) L3MBTL1CYP4F2CYP4A11JAK2ACHE
SCHEMBL18281316 0.79 L3MBTL1 (0.44) L3MBTL1ACHEMKNK1MKNK2CCNC
SCHEMBL30163007 0.79 NTRK2 (0.43) L3MBTL1NAMPTHDAC1HDAC6HDAC3
SCHEMBL24841255 0.78 JAK3 (0.47) L3MBTL1CYP4F2CYP4A11JAK1JAK3
SCHEMBL30162871 0.78 L3MBTL1 (0.43) L3MBTL1JAK3ACHEMKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023277517-A1 ACYCLIC NUCLEIC ACID MIMIC COMPRISING PENTACYCLIC BASE 동아대학교 산학협력단 2023-01-05 WO disclosed
WO-2023277517-A1 ACYCLIC NUCLEIC ACID MIMIC COMPRISING PENTACYCLIC BASE 동아대학교 산학협력단 2023-01-05 WO disclosed