Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.37 |
| ▸ | WNT3A | P56704 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798144 | 0.88 | ALDH1A1 (0.42) | PRMT5WDR77SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL771949 | 0.88 | ALDH1A1 (0.42) | PRMT5WDR77SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL771948 | 0.88 | ALDH1A1 (0.42) | PRMT5WDR77SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL2412606 | 0.84 | ALDH1A1 (0.42) | PRMT5WDR77SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL2412605 | 0.84 | ALDH1A1 (0.42) | PRMT5WDR77SLC6A4OPRK1ALDH1A1 | |
| SCHEMBL1703624 | 0.81 | DRD2 (0.53) | CYP2D6SLC6A4ALDH1A1MAPTKMT2A | |
| SCHEMBL12277410 | 0.79 | NR1H2 (0.43) | OPRK1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL15970845 | 0.70 | ACACB (0.41) | ABCB1ROCK2PRMT5WDR77SLC6A2 | |
| SCHEMBL12277442 | 0.70 | NR1H2 (0.67) | MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL2410813 | 0.70 | NR1H2 (0.67) | MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376484-A1 | OXADIAZOLE FUSED HETEROCYCLIC DERIVATIVES USEFUL FOR THE TREATMENT OF MULTIPLE SCLEROSIS | Merck Serono S.A. (CH) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010069949-A1 | OXADIAZOLE FUSED HETEROCYCLIC DERIVATIVES USEFUL FOR THE TREATMENT OF MULTIPLE SCLEROSIS | MERCK SERONO S.A. (CH) | 2010-06-24 | — | — | WO | disclosed |