SCHEMBL24844922

SCHEMBL24844922

CCOC(=O)C1CC1c1ccc(Cn2ccnc2)cc1C

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 8/20 0.48
CYP11B1 P15538 3/20 0.44
CYP11B2 P19099 3/20 0.44
CYP19A1 P11511 7/20 0.42
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
PGGT1B P53609 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24844927 0.90 TBXAS1 (0.46) TBXAS1CYP11B1CYP11B2CYP19A1
SCHEMBL24844864 0.90 TBXAS1 (0.46) TBXAS1CYP11B1CYP11B2CYP19A1
SCHEMBL24844868 0.87 TBXAS1 (0.48) TBXAS1CYP11B1CYP11B2CYP19A1
SCHEMBL24845013 0.87 TBXAS1 (0.48) TBXAS1CYP11B1CYP11B2CYP19A1
SCHEMBL24845630 0.87 TBXAS1 (0.48) TBXAS1CYP11B1CYP11B2CYP19A1
SCHEMBL24844928 0.82 MAP3K5 (0.41)
SCHEMBL24844931 0.82 KMT2A (0.41)
SCHEMBL24845175 0.79 TBXAS1 (0.48) TBXAS1CYP11B1CYP11B2CYP19A1
SCHEMBL24844923 0.78 CA2 (0.47)
SCHEMBL24844920 0.77 CA1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023274257-A1 IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF 诸葛国琴 2023-01-05 WO disclosed