Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.55 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24845648 | 0.84 | CYP11B1 (0.58) | CYP11B1CYP11B2PHF8HTTSMN1; SMN2 | |
| SCHEMBL24845216 | 0.84 | CYP11B1 (0.58) | CYP11B1CYP11B2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19936854 | 0.83 | HPGDS (0.51) | CYP11B1CYP11B2PHF8NPC1KDM4C | |
| SCHEMBL18961310 | 0.81 | CYP11B1 (0.55) | CYP11B1CYP11B2PHF8HTTSMN1; SMN2 | |
| SCHEMBL6528673 | 0.81 | PHF8 (0.57) | CYP11B1CYP11B2PHF8HTTSMN1; SMN2 | |
| SCHEMBL6528669 | 0.81 | CYP11B1 (0.55) | CYP11B1CYP11B2PHF8HTTSMN1; SMN2 | |
| SCHEMBL24845096 | 0.81 | CYP11B1 (0.55) | CYP11B1CYP11B2HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28368152 | 0.78 | CYP11B1 (0.51) | CYP11B1CYP11B2PHF8HTTSMN1; SMN2 | |
| SCHEMBL21314995 | 0.77 | KDM4C (0.50) | CYP11B1CYP11B2PHF8HTTSMN1; SMN2 | |
| SCHEMBL30504034 | 0.77 | KDM4C (0.50) | CYP11B1CYP11B2PHF8HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274257-A1 | IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF | 诸葛国琴 | 2023-01-05 | — | — | WO | disclosed |