Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897511 | 0.85 | GRIK1 (0.42) | GRIK1GRIK2TP53EP300 | |
| SCHEMBL800569 | 0.85 | GRIK1 (0.42) | GRIK1GRIK2TP53EP300 | |
| SCHEMBL28162706 | 0.81 | GRIK1 (0.44) | GRIK1GRIK2TP53EP300 | |
| SCHEMBL6000457 | 0.79 | GRIK1 (0.38) | GRIK1GRIK2 | |
| SCHEMBL7559349 | 0.79 | GRIK1 (0.38) | GRIK1GRIK2 | |
| SCHEMBL7178549 | 0.79 | EP300 (0.47) | GRIK1TP53EP300 | |
| SCHEMBL8022454 | 0.76 | CHRM1 (0.38) | GRIK1GRIK2EP300 | |
| SCHEMBL8514553 | 0.76 | GRIK1 (0.40) | GRIK1GRIK2 | |
| SCHEMBL2857650 | 0.74 | — | — | |
| SCHEMBL5463147 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376053-B1 | POROUS POLYMER COATING FOR TOOTH WHITENING | JOHNSON & JOHNSON CONSUMER INC (US) | 2019-09-25 | — | — | EP | disclosed |
| US-9296846-B2 | Porous polymer coating for tooth whitening | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-03-29 | — | — | US | disclosed |
| EP-2376053-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | McNeil-PPC, Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010080501-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | MCNEIL-PPC, INC. (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100158960-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | KENVUE BRANDS LLC | 2010-06-24 | — | — | US | disclosed |
| EP-0755951-B1 | Acrylic ester derivative and producing process of the same and acrylic-ester-based polymer | NIPPON CATALYTIC CHEM IND (JP) | 2003-02-05 | — | — | EP | disclosed |
| US-5783678-A | HYDROPHILIC | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-07-21 | — | — | US | disclosed |
| EP-0699179-B1 | (2-CARBOXY-3-HYDROXY-PROPYL)-IMINODIACETIC ACID AND DERIVATIVES | AKZO NOBEL NV (NL) | 1998-02-18 | — | — | EP | disclosed |
| EP-0755951-A2 | Acrylic ester derivative and producing process of the same and acrylic-ester-based polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-01-29 | — | — | EP | disclosed |
| WO-1994026691-A1 | (2-CARBOXY-3-HYDROXY-PROPYL)-IMINODIACETIC ACID AND DERIVATIVES | AKZO NOBEL N.V. (NL) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158960-A1 | POROUS POLYMER COATING FOR TOOTH WHITENING | MMP20, COL14A1, POLR1C | GRIK1 1492/4885GRIK2 1524/4885TP53 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.