MMP20

Matrix metalloproteinase-20 · O60882 · MMP20 on Sugi Atlas →

246 patent compounds predicted against MMP20, 197 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Marimastat (SCHEMBL34033)	1.00	1/20
Marimastat (SCHEMBL134999)	1.00	1/20
Marimastat (SCHEMBL1821430)	1.00	1/20
Marimastat (SCHEMBL8189167)	1.00	1/20
Marimastat (SCHEMBL8193003)	1.00	1/20
Marimastat (SCHEMBL13253251)	1.00	1/20
Marimastat (SCHEMBL13575773)	1.00	1/20
Marimastat (SCHEMBL17799241)	1.00	1/20
Marimastat (SCHEMBL20793036)	1.00	1/20
Marimastat (SCHEMBL31231856)	1.00	1/20
Marimastat (SCHEMBL7931107)	0.97	1/20
Marimastat (SCHEMBL7933374)	0.97	1/20
SCHEMBL7983019	0.78	1/20
SCHEMBL19286781	0.78	1/20
SCHEMBL8026827	0.77	1/20
SCHEMBL9714151	0.77	1/20
SCHEMBL17128737	0.77	1/20
SCHEMBL1847104	0.75	1/20
SCHEMBL6435806	0.75	1/20
SCHEMBL9714274	0.75	1/20

Clinical trials — most relevant to MMP20 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma	PHASE2	UNKNOWN
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Screening and Identification of Biomarkers for High Myopia by a Rapid Method	nan	UNKNOWN
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
Matrix Metalloproteinase (MMP) in Heart Failure	nan	COMPLETED
Role and Expression of MXRA5 in Placental Connective Tissue Remodelling in Preeclampsia	nan	UNKNOWN
Biomarkers for Prognosis of Glioblastoma (GBM)	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
LRP1 and Colon Cancer	nan	UNKNOWN
Influence of Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis	nan	COMPLETED
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease	nan	NOT_YET_RECRUITING
The Impact of Pregnancy and Pregnancy-associated Hypertension on Human Uterine Myometrial Artery Reactivity	nan	WITHDRAWN
Hypoxia-induced Autophagy in the Pathogenesis of MAP	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a MMP20 binder may also engage these)

Protein	Name	Similarity
P57748	—	1.000	P57748 →
O18767	—	1.000	O18767 →
P79287	—	1.000	P79287 →
Q10835	—	1.000	Q10835 →
P07152	—	1.000	P07152 →
O55123	—	1.000	O55123 →
Q63341	—	1.000	Q63341 →
MMP1	Interstitial collagenase	0.999	landscape →
P53690	—	0.999	P53690 →
O62806	—	0.998	O62806 →
Q10739	—	0.998	Q10739 →
Q95220	—	0.998	Q95220 →
P34960	—	0.997	P34960 →
MMP12	Macrophage metalloelastase	0.997	landscape →
MMP3	Stromelysin-1	0.997	landscape →
Q28397	—	0.997	Q28397 →
P79227	—	0.997	P79227 →
Q5RES1	—	0.997	Q5RES1 →
O70138	—	0.997	O70138 →
MMP10	Stromelysin-2	0.997	landscape →
O88766	—	0.997	O88766 →
Q9GKE1	—	0.996	Q9GKE1 →
MMP14	Matrix metalloproteinase-14	0.996	landscape →
P03957	—	0.996	P03957 →
O77656	—	0.996	O77656 →
P23097	—	0.996	P23097 →
Q9GLE4	—	0.996	Q9GLE4 →
P28053	—	0.996	P28053 →
Q6Y4Q5	—	0.996	Q6Y4Q5 →
P28862	—	0.995	P28862 →