Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28812503 | 0.89 | FKBP1A (0.57) | FKBP1A | |
| SCHEMBL19230481 | 0.89 | FKBP1A (0.57) | FKBP1A | |
| SCHEMBL21643229 | 0.88 | FKBP1A (0.52) | FKBP1A | |
| SCHEMBL20850015 | 0.88 | FKBP1A (0.52) | FKBP1A | |
| SCHEMBL19230455 | 0.88 | FKBP1A (0.52) | FKBP1A | |
| SCHEMBL18567011 | 0.87 | FKBP1A (0.64) | FKBP1A | |
| SCHEMBL18352032 | 0.85 | FKBP1A (0.61) | FKBP1A | |
| SCHEMBL21690552 | 0.83 | FKBP1A (0.45) | FKBP1A | |
| SCHEMBL29730863 | 0.81 | FKBP1A (0.61) | FKBP1A | |
| SCHEMBL4679960 | 0.80 | FKBP1A (1.00) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | RICTOR, FKBP14, MTOR | FKBP1A 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.