Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24847147 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL228551 | 0.67 | — | — | |
| SCHEMBL4338671 | 0.66 | MME (0.36) | ALDH1A1 | |
| SCHEMBL4339726 | 0.66 | RXFP1 (0.36) | ALDH1A1 | |
| SCHEMBL8352040 | 0.65 | — | — | |
| SCHEMBL16318985 | 0.65 | — | — | |
| SCHEMBL4331086 | 0.64 | RXFP1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL24847188 | 0.64 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24186623 | 0.63 | — | — | |
| SCHEMBL20716496 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250360141-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2025-11-27 | — | — | US | disclosed |
| US-12433897-B2 | Pyridine derivatives with n-linked cyclic substituents as cGAS inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-10-07 | — | — | US | disclosed |
| CN-119119063-A | Pyridine derivatives having N-linked cyclic substituents as cGAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119119062-A | Pyridine derivatives having N-linked cyclic substituents as cGAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20240342186-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2024-10-17 | — | — | US | disclosed |
| CN-117337292-A | Pyridine derivatives having N-linked cyclic substituents as cGAS inhibitors | 勃林格殷格翰国际有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-20230000878-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-01-05 | — | — | US | disclosed |
| US-20230000878-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240342186-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | CGAS, GLS2, GMPS | ALDH1A1 1112/4885LMNA 640/4885SMN1; SMN2 2556/4885 |
| US-20250360141-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | CGAS, GLS2, GMPS | ALDH1A1 1206/4885LMNA 606/4885SMN1; SMN2 2437/4885 |
| US-20230000878-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | CGAS, GLS2, GMPS | ALDH1A1 1112/4885LMNA 640/4885SMN1; SMN2 2556/4885 |
| US-12433897-B2 | Pyridine derivatives with n-linked cyclic substituents as cGAS inhibitors | CGAS, GLS2, GMPS | ALDH1A1 1112/4885LMNA 640/4885SMN1; SMN2 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.