Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27172952 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24534029 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL22259417 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL22449838 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL21814069 | 0.77 | GABRA1 (0.31) | — | |
| SCHEMBL31616170 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL20464429 | 0.71 | ADA (0.35) | — | |
| SCHEMBL22449854 | 0.71 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL23364819 | 0.71 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18418129 | 0.71 | CACNA1H (0.38) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000878-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000878-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | CGAS, GLS2, GMPS | ALDH1A1 1112/4885SMN1; SMN2 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.