Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24843012 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL29947996 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL24845794 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL24846116 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31673315 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL1310612 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL30960342 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL15304530 | 0.75 | KMT2A (0.62) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL29850525 | 0.75 | KMT2A (0.62) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL31673212 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000878-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000878-A1 | PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS | CGAS, GLS2, GMPS | SMN1; SMN2 2556/4885KMT2A 4804/4885MEN1 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.