Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27238640 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL24843012 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL29947996 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL24845794 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL24846116 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL24846161 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL27238590 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL30914147 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL31673315 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL1310612 | 0.68 | SMN1; SMN2 (0.62) | SMN1; SMN2PIM1CSNK2A2CSNK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615849-A1 | CYCLIC BENZIMIDAZOLE DERIVATIVES AS CGAS INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| CN-120202206-A | Cyclic benzimidazole derivatives as cGAS inhibitors | 勃林格殷格翰国际有限公司 | 2025-06-24 | — | — | CN | disclosed |